Vygenerované: 24.06.2026 18:12:12
Súhrn: Adolescents with irregular sleep schedules, social jet lag, or insomnia symptoms had significantly higher odds of poorer overall health and hospitalization 7 years later, even after adjusting for baseline health status and sociodemographic factors The results of the longitudinal study suggest that sleep health during adolescence may have lasting effects on physical well-being, underscoring the importance of identifying and addressing sleep problems early “Improving youth sleep regularity and insomnia symptoms among youth may protect young adult health, well-being, and overall quality of life,” lead author Gina M.
Doplnenie: Mathew, PhD, with Stony Brook University, Stony Brook, New York, said in a statement.
Súhrn: TOPLINE: Patients with episodic or chronic migraine who responded to preventive treatment with anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) or botulinum toxin (BoNT) showed a significantly greater improvement in interictal executive cognitive performance than those who did not respond, regardless of the treatment type METHODOLOGY: - Researchers conducted an observational two-centre cohort study to evaluate whether preventive treatment with anti-CGRP mAbs or BoNT improves interictal cognitive performance in patients with migraine and whether changes in performance differ between treatment responders and non-responders - Participants underwent two comprehensive cognitive evaluations at baseline and after 3-6 months of treatment, covering four domains: episodic memory, language, attention and processing speed, and executive functions.
Doplnenie: 7% women), comprising 58 with chronic migraine and 32 with episodic migraine; 64 patients were treated with anti-CGRP mAbs, and 26 were treated with BoNT.
Súhrn: METHODOLOGY: - Researchers conducted an observational study and analysed data from Clinical Practice Research Datalink Aurum, a large longitudinal database of records from primary care practices across England, to establish the point prevalence of recorded ADHD diagnoses as of June 2025 TOPLINE: Diagnosis rates for attention-deficit/hyperactivity disorder (ADHD) in England were below global prevalence estimates across all age groups, with a recorded prevalence at 1 Male individuals were diagnosed at a rate of 1.
Doplnenie: The gap between recorded diagnosis and published prevalence estimates varied widely from approximately 28.
Súhrn: An adaptive deep brain stimulation (aDBS) system, personalized to sync with the walking cycle, improved gait stability and reduced falls in patients with Parkinson’s disease (PD), a small feasibility study showed In laboratory testing, the system improved gait symmetry and consistency, while a blinded home crossover study showed a reduction in falls without compromising overall motor control Wang, MD, PhD, associate professor of neurological surgery at the University of California, San Francisco (UCSF), told Medscape Medical News.
Doplnenie: “Walking is one of the most dynamic human behaviors,” senior investigator Doris D.
Súhrn: Once men with metastatic hormone-sensitive prostate cancer start androgen deprivation therapy (ADT) and an androgen receptor pathway inhibitor (ARPI), the conventional thinking is that they stay on them indefinitely But treatment comes at the cost of considerable side effects, including fatigue, hot flashes, sexual problems, weight gain, and others Their use has also been associated with increased risks for cardiovascular disease, osteoporosis, and depression.
Doplnenie: Giving men a break from ADT plus ARPI could improve their quality of life, and the results of the phase 2 A-DREAM study, which were reported at the American Society of Clinical Oncology (ASCO) 2026, suggest it can be safe to do so.