Denný súhrn - Zdravotnícke a vedecké zaujímavosti

Súhrn: Muscle loss during glucagon-like peptide-1 (GLP-1) receptor agonist therapy was the focus of a lively debate at the American Diabetes Association (ADA) 2026 Scientific Sessions held in June A subsequent study reanalyzed the reported 39% lean mass loss by accounting for the fluid and protein normally lost from adipose tissue, reducing the figure to 30% Additional caution applies to patients with weight cycling, metabolic dysfunction-associated steatohepatitis (MASH), obstructive sleep apnea, cardiovascular disease, or body mass index (BMI) under 30.

Súhrn: TOPLINE Adding atezolizumab to stereotactic body radiation therapy (SBRT) did not improve survival outcomes in patients with early-stage, medically inoperable non-small cell lung cancer (NSCLC), according to a phase 3 trial that closed early for futility METHODOLOGY - SBRT emerged as the standard of care for early-stage, medically inoperable NSCLC following clinical trials showing high rates of local control and low toxicity A phase 2 trial found that adding immunotherapy to SBRT improved event-free survival, but no phase 3 data have been published until now.

Súhrn: Regular cannabis users have long shown lower rates of obesity and type 2 diabetes despite the appetite-boosting "munchies" effect, a paradox that a new mouse study helps explain The data are preclinical and don't support cannabis use for weight or metabolic health The mouse study published in The Journal of Physiology points to a possible mechanism: disrupted "cross talk" between fat tissue and the pancreas, suggesting nonpsychoactive plant compounds, not delta-9-tetrahydrocannabinol (THC), may be doing the metabolic work.

Súhrn: Certain drug combinations are common but often unrecognized contributors to drug-related harm among older adults, setting off prescribing cascades that add unnecessary costs to the healthcare system, a new cohort study suggests "A prescribing cascade occurs when a drug is prescribed, a drug-related adverse event develops that is misinterpreted as a new medical condition, and a second, potentially inappropriate drug is started to manage the adverse event," Paula Rochon, MD, director of research at the Weston and O'Born Centre for Mature Women's Health at Sinai Health in Toronto, and her research manager, Joyce Li, told Medscape News Canada The list "provides an important expert-informed tool for clinicians and researchers to identify potentially inappropriate prescribing patterns and improve medication safety in older adults," Rochon and Li said.

Súhrn: Ja som to zažila Ja som tiež skoro umrela od duševnej bolesti Ale som tu… aby som vám povedala, že v tom nie ste sami.