Vygenerované: 19.09.2026 19:43:46
Súhrn: Through a search of the FDA's Adverse Event Monitoring System and the medical literature, the agency said it identified 129 cases of adverse events when deoxycholic acid injection was used outside the chin area, including blurred or reduced vision when injected around the eyes and facial paresis and paresthesia But the label has been updated to note that "some nodules and masses may not resolve and medical intervention may be required Citing what it called "newly identified risks," the FDA is reinforcing its warnings about adverse events associated with injections of deoxycholic acid (Kybella).
Doplnenie: Through a search of the FDA's Adverse Event Monitoring System and the medical literature, the agency said it identified 129 cases of adverse events when deoxycholic acid injection was used outside the chin area, including blurred or reduced vision when injected around the eyes and facial paresis and paresthesia.
Súhrn: TOPLINE An observational imaging study using data from over 27,500 CT scans found that normalising epicardial adipose tissue volume (EATV) to total heart volume (EATVh), with a proposed cutoff of 0 1, effectively ruled out obstructive coronary artery disease (CAD) with a negative predictive value (NPV) of 97 METHODOLOGY - Researchers analysed data of 25,155 participants (50.
Doplnenie: 7% women) aged 50-64 years from a subset of the SCAPIS cohort and 2482 symptomatic patients (58.
Súhrn: METHODOLOGY - This cross-sectional study estimated the prevalence of resilience, self-silencing, depression, and antiretroviral treatment adherence among racially and ethnically minoritized women living with HIV during the COVID pandemic and examined the associations of these psychosocial factors with each other and with pandemic-related stress - Participants completed staff-administered questionnaires that included demographic and clinical questions and validated measures of antiretroviral treatment adherence, resilience, depression, and self-silencing TAKEAWAY - Overall, 33% of the participants had low resilience, 25% screened positive for mild-to-severe depression, and 36% reported low antiretroviral treatment adherence; the mean self-silencing score was 66.
Doplnenie: - They included 85 women (mean age, 37.
Súhrn: TOPLINE Paediatric and young patients with inflammatory bowel disease (IBD) and concomitant attention-deficit/hyperactivity disorder (ADHD) or autism showed no difference in the risk for severe disease at 1 year after diagnosis compared with those with IBD alone METHODOLOGY - Researchers conducted a nationwide registry-based cohort study to assess the effect of ADHD or autism on disease activity in paediatric and young patients with IBD - Disease activity was categorised as remission, mild‐moderate disease activity, or severe disease activity.
Doplnenie: - They included 7514 patients aged 6-24 years at IBD diagnosis from 1996 to 2022 using data from Danish national registries, of whom 785 had IBD with ADHD or autism and 6729 had IBD alone.
Súhrn: TOPLINE A retrospective structural MRI study found that "hot" or affectively driven suicidal ideation (SI) among patients with major depressive disorder (MDD) was associated with reduced thalamo-pallidal volumes METHODOLOGY - Researchers retrospectively analysed structural MRI data from 263 individuals with MDD experiencing a current major depressive episode at Henri Laborit Hospital in Poitiers, France, between 2014 and 2025 - Researchers analysed potential associations between ideation subtypes and brain volumes, adjusting for age, sex, intracranial volume, depression severity measured using the Beck Depression Inventory-Short Form, and history of suicide attempt.
Doplnenie: - Participants were categorised into three groups based on the Montgomery-Åsberg Depression Rating Scale suicide item: those with no SI (n = 207), those with hot SI (n = 49), and those with cold SI (n = 7).